PRF Treatment
Platelet-rich fibrin from your own blood is injected to rejuvenate under-eyes, skin, and hair.
PRF Treatment near you
Charles
Lee, MD
Carlo
Honrado, MD
James
Pearson, MD
Hannah
Vu, MD
Alexis
Furze, MD,
Al
Valmadrid, MD
Gabriel
Chiu
Lisa
Cassileth, MD
Amy
Hsu, MD
Kian
Karimi, MD
Behrooz
Torkian, MD
Stephen
Bresnick, MD
George
Sanders, MD
Neal
Handel
Richard
Lee, MD
Kevin
Sadati, DO
Giriraj
Sharma, MD,
Taylor
Pollei, MD
Geoffrey
Trenkle, DO
Charles
Hsu, MD
Won
Bae, MD
Steven
Lee, MD
David
Kahng
Andrew
Choi, MD
Jennifer
Keagle
Dennis
Bang, MD
Harry
Schwartz, MD
Tsung-Yen
Hsieh, MD
Michael
Bublik, MD
Peter
Ashjian, MD
Stephen
Cabalatungan
Debra
Stafford, MD
Konstantin
Salkinder, MD
Nance
Yuan
Jason
Hamilton, MD
Andre
Panossian, MD
Omar
Hussain, MD
Mark
Solomon, MD
Mohammad
Khosravi, MD
David
Alessi, MD
Kevin
Ruhge, MD
PRF Treatment: making the decision
What the price actually covers
Honest risks
- Bruising and swelling at draw and injection sites
- Subtle, natural-pace results — not a filler replacement
- Multiple sessions before you judge it
Are you a good candidate?
- Under-eye hollows, early hair thinning, skin quality
- Wanting a natural, no-synthetic option
- Patient with gradual results
Six questions for every consult
- Are you board-certified, and in what specialty? (Verify it — don't just ask.)
- How many of this exact procedure did you do in the last 12 months?
- Can I see before/afters of patients with my anatomy or skin type?
- Who handles complications, and what's your revision policy and fee?
- Where is the procedure done, and is the facility accredited?
- What results would you consider realistic for me — and what won't this fix?
Verify before you book
PRP vs PRF — same blood draw, different products
Both start with your own blood; the preparation differs, and so does what ends up in the syringe. The evidence comparison below comes from a 2025 systematic review of the periorbital literature and a meta-analysis of the hair-loss trials — small studies, honestly summarized.
| PRP | PRF | |
|---|---|---|
| Preparation | Double spin, with an anticoagulant | Single slower spin, no anticoagulant — fully autologous |
| The product | Platelets suspended in plasma | A fibrin scaffold trapping platelets and white cells |
| Growth-factor release | Rapid and transient | Prolonged — up to two weeks |
| Hair-loss evidence | 9 RCTs, 238 patients: density improved vs placebo at 3 and 6 months | No comparable RCT meta-analysis exists yet |
| Under-eye evidence | Stronger for pigmentation; sustained around 6 months | Better for texture and fine lines; gains often faded by 6 months |
PRP occupies an unusual spot: the FDA's 2020 guidance states that blood drawn from you and returned to you as platelet-rich plasma is a blood product, not a human cell-and-tissue product, so the tissue-regulation framework doesn't apply to it. What that means in practice is that no FDA review stands behind any specific aesthetic indication — the centrifuge kits are devices, but the treatment claims rest on the clinic, not on an approval. Ask which preparation protocol the clinic uses and how many sessions they propose; the literature's main criticism of this field is that no two clinics do it the same way.
Source: FDA — Regulatory Considerations for HCT/Ps (July 2020) ↗Med spas by metro
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Patient reviews
PRF Treatment: common questions
How much does PRF treatment cost?
No professional body publishes a PRF-specific figure. The nearest sourced number is for PRP, its older sibling: the ASPS 2023 fee table lists platelet-rich plasma at an average of $755 per treatment. PRF is typically sold in multi-session courses for hair, under-eyes, or as a microneedling add-on, so compare full-course prices. Given how modest and temporary the measured benefits are in the literature, the sessions-times-price math deserves honest attention before you commit.
What's the difference between PRP and PRF?
Both are your own blood, drawn and spun. PRP uses an anticoagulant and a double spin, producing platelets in plasma that release growth factors quickly. PRF skips the anticoagulant and uses a single slower spin, producing a fibrin scaffold that releases growth factors for up to two weeks. Whether that difference matters clinically is unproven: a 2025 systematic review found current evidence does not support the superiority of either, with PRF showing better texture results under the eyes but fading by six months, and PRP holding the stronger evidence for hair-density improvement.
Does PRF actually work?
Honestly: the evidence is thin, and thinner for PRF than PRP. The hair-loss data that exists supports PRP — nine randomized trials showed density gains at three and six months versus placebo. For under-eye treatment, PRF improved texture and fine lines in small studies, with the gains often faded by six months. Side effects across the literature were transient — swelling, redness, bruising. It's a low-risk treatment with modest, temporary, honestly-uncertain benefits; a clinic that presents it that way is being straight with you, and one promising dramatic regeneration is ahead of anything published.